Copper Peptide AHK-Cu (AHKCu)

Healing Preclinical

AHK-Cu (Alanine-Histidine-Lysine-Copper) is a copper-binding tripeptide that has gained attention for its hair growth-stimulating properties. While related to the well-known GHK-Cu peptide, AHK-Cu has been specifically studied for its effects on hair follicle biology. Research has shown that AHK-Cu can stimulate the proliferation of dermal papilla cells — the key signaling cells at the base of hair follicles that control hair growth cycling.

Key Data

Research Status
Preclinical
Half-Life
Topical (not systemically relevant)
Administration
Topical
Typical Dosage
1-3% in topical formulations
Molecular Weight
403.9 Da (with copper)
Molecular Formula
C13H24N5O4Cu

Mechanism of Action

AHK-Cu binds copper(II) ions and delivers them to hair follicles and skin cells, stimulating VEGF production, enhancing dermal papilla cell proliferation, and promoting extracellular matrix remodeling. It activates signaling pathways involved in hair follicle cycling.

Reported Benefits

All information is presented for Research Use Only (RUO). Not medical advice.

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