Epithalon (EPT)

Anti-Aging Preclinical

Epithalon is the synthetic version of the polypeptide Epithalamin, naturally produced in humans via the pineal gland. This tetrapeptide (Ala-Glu-Asp-Gly) has been extensively studied by Russian scientists for its potential anti-aging properties. The peptide works primarily by stimulating telomerase activity, which helps maintain telomere length during cell division. As cells age, their telomeres progressively shorten, eventually leading to cellular senescence or apoptosis. By promoting telomerase activity, Epithalon research suggests the potential to extend cellular lifespan. Additionally, Epithalon plays a role in regulating melatonin production and the neuroendocrine system, which affects sleep patterns, immune function, and overall physiological balance.

Key Data

Research StatusPreclinical
Half-LifeUnknown
AdministrationSubcutaneous injection
Typical Dosage5-10 mg daily
Molecular Weight390.35 Da
Molecular FormulaC14H22N4O9

Mechanism of Action

Telomerase activation, melatonin regulation, antioxidant activity.

Reported Benefits

All information is presented for Research Use Only (RUO). Not medical advice.

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