GHK-Cu (Copper peptide GHK-Cu, or Glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. GHK-Cu levels decline significantly with age, from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60. The peptide plays crucial roles in wound healing, tissue remodeling, and skin regeneration. GHK-Cu stimulates collagen synthesis, promotes angiogenesis, attracts immune cells to injury sites, and has antioxidant and anti-inflammatory properties. Its ability to stimulate glycosaminoglycan synthesis and modulate gene expression has made it popular in cosmetic and wound healing research.
| Research Status | Preclinical |
|---|---|
| Half-Life | 4-6 hours |
| Administration | Subcutaneous or topical |
| Typical Dosage | 1-3 mg |
| Molecular Weight | 403.9 Da (with copper) |
| Molecular Formula | C14H24CuN6O4 |
Copper delivery for enzyme function, stimulates collagen and glycosaminoglycan synthesis, antioxidant gene activation.
All information is presented for Research Use Only (RUO). Not medical advice.