GHK-Cu (Copper peptide GHK-Cu, or Glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. GHK-Cu levels decline significantly with age, from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60. The peptide plays crucial roles in wound healing, tissue remodeling, and skin regeneration. GHK-Cu stimulates collagen synthesis, promotes angiogenesis, attracts immune cells to injury sites, and has antioxidant and anti-inflammatory properties. Its ability to stimulate glycosaminoglycan synthesis and modulate gene expression has made it popular in cosmetic and wound healing research.
Key Data
Mechanism of Action
Copper delivery for enzyme function, stimulates collagen and glycosaminoglycan synthesis, antioxidant gene activation.
Reported Benefits
All information is presented for Research Use Only (RUO). Not medical advice.