GHRP6
Growth Hormone Releasing Peptide-6, the first generation GHRP known for strong appetite stimulation. In a study of 6 healthy men, 1 microg/kg IV produced a peak GH of ~55 microg/L.
Regulatory status (as of Sept 2026)
Not FDA-approved. Not among the peptides listed in the April 2026 503A Category 2 removals or the July 2026 PCAC votes; no lawful compounded pathway. WADA-prohibited (PMID 26578461).
See the FDA peptide regulatory tracker · Read our July 27, 2026 dispatch on the FDA PCAC peptide vote6 studies referenced · Last reviewed Oct 1, 2026 · Reviewed by The Peptide Dispatch Editorial Team · How we research & label content
GHRP-6 is a compound with only early, small human studies so far. Growth Hormone Releasing Peptide-6, the first generation GHRP known for strong appetite stimulation.
| Half-life | Not established in published research |
|---|---|
| How it's given in studies | Subcutaneous injection |
| Research stage | Phase 1 / early human |
| Dosing | Published research: 1 microgram/kg body weight IV bolus, and 5, 15 and 30 micrograms/kg intranasally, in 6 healthy men… details1 microgram/kg body weight IV bolus, and 5, 15 and 30 micrograms/kg intranasally, in 6 healthy men (dose-related GH rise). Other human endocrine studies used GHRP-2/GHRH infusions at microgram/kg doses.Community-reportedCommunity-reported: 100–300 mcg, subcutaneous injection |
Published-research dosing is what was given in the cited studies (species and units as reported). Community-reported dosing is what users describe, not from clinical studies. Neither is a recommendation. Not medical advice.
Where each point comes from: Clinicalhuman trials and FDA labels Lab / animalrodent, cell and ex vivo studies Community-reporteduser experience and commonly used protocols, not from clinical studies
In plain terms: It acts like the hunger hormone ghrelin to trigger growth hormone release. Ghrelin mimetic (growth hormone secretagogue) that stimulates GH release; in healthy men it raised GH, with slight increases in prolactin and cortisol (Hayashi 1991). Ghrelin and many synthetic secretagogues are described as stimulating appetite (review, Cordido 2009).
How to read this: Each item below is an effect observed in research subjects in the cited studies — think of Dexter, our stand-in research subject. These are findings from the literature, not results you should expect, and not medical advice.
Community-reportedCommonly reported doses range from 100 to 300 mcg (subcutaneous injection). This is not a recommendation.
Side effects reported in studies are listed separately below.
Community reports are anecdotal, vary widely in product quality and purity, and are not medical advice. Talk to a licensed provider.
Beyond GH release, GHRP-6 has been studied in rat myocardial infarction and doxorubicin cardiotoxicity models. GHRPs such as hexarelin bind CD36 in addition to GHSR-1a (rat data).
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| Peptide | Half-Life | Route | Research Status |
|---|---|---|---|
| GHRP-6 | No published PK data found | Subcutaneous injection | Phase 1 / early human |
| CJC-1295 (no DAC) | No published PK data found | Subcutaneous injection | Preclinical (animal) |
| CJC-1295 (with DAC) | 6-8 days | Subcutaneous injection | Phase 1 / early human |
| GHRP-2 | No published PK data found | Subcutaneous injection | Phase 1 / early human |
| Hexarelin | No published PK data found | Subcutaneous injection | Phase 1 / early human |
Values reflect figures reported in published research. Compare any peptides side-by-side →
This peptide belongs to the Growth Hormone category. View All Growth Hormone Peptides
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Dosing, half-life figures, and mechanism descriptions on this page are compiled from peer-reviewed published research, with the species and study type stated where reported. Figures labeled “Dosing used in published research” describe what was given in those studies and do not constitute dosing recommendations for any human use. Each cited paper is listed with DOI and PubMed links in the References section above. Found an error? Contact us.