Gonadorelin is a synthetic decapeptide identical to naturally occurring gonadotropin-releasing hormone (GnRH or LHRH). Produced in the hypothalamus, GnRH controls the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland, which in turn regulate gonadal function. Gonadorelin is used clinically for diagnostic testing of pituitary function and therapeutically in both pulsatile (to stimulate) and continuous (to suppress) modes. In males, LH stimulates testosterone production; in females, FSH and LH control ovulation and estrogen/progesterone synthesis. Gonadorelin is essential for fertility treatments and hormonal assessments.
Key Data
Mechanism of Action
Activates GnRH receptors in pituitary to release gonadotropins in pulsatile manner.
Reported Benefits
All information is presented for Research Use Only (RUO). Not medical advice.