Hexarelin is a synthetic hexapeptide growth hormone secretagogue and one of the most potent GH-releasing peptides developed. It acts on the ghrelin receptor (GHS-R1a) to stimulate growth hormone release from the pituitary gland. Hexarelin is distinguished by its notably strong cardioprotective properties, independent of its GH-releasing effects. Research has shown Hexarelin protects cardiac tissue through activation of specific cardiac receptors and modulation of calcium handling. Unlike some other GHRPs, Hexarelin maintains its GH-releasing efficacy with repeated administration, though it may still be subject to some desensitization over extended use periods.
Key Data
Mechanism of Action
Highly potent ghrelin receptor agonist with strongest GH release among GHRPs. Causes rapid receptor desensitization.
Reported Benefits
All information is presented for Research Use Only (RUO). Not medical advice.