Humanin (HN)

Anti-Aging Preclinical

Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026

TL;DR — Humanin at a Glance

Humanin (HN) is a anti-aging peptide, at the preclinical stage in the published literature. Mitochondria-derived peptide with cytoprotective and anti-apoptotic effects. Natural levels decline with age.

Mitochondria-derived peptide with cytoprotective and anti-apoptotic effects. Natural levels decline with age.

Key Data

Research StatusPreclinical
Half-LifeUnknown
AdministrationSubcutaneous injection
Doses Reported in Published Studies1-5 mg

Mechanism of Action

Binds to multiple receptors including IGFBP-3 and BAX, preventing apoptosis and protecting cells from stress.

Reported Benefits

Frequently Asked Questions

What is Humanin?

Mitochondria-derived peptide with cytoprotective and anti-apoptotic effects. Natural levels decline with age.

How does Humanin work?

Binds to multiple receptors including IGFBP-3 and BAX, preventing apoptosis and protecting cells from stress.

What is the research status of Humanin?

Humanin is at the following stage in the published literature: Preclinical. All information is for research and educational purposes only.

What is the half-life of Humanin?

Reported half-life: Unknown.

How is Humanin administered in research?

Reported administration route in the literature: Subcutaneous injection. This is not a recommendation for human use.

Educational content, not medical advice. Effects described are drawn from cited research in study subjects.

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