MK-677 (Ibutamoren) (MK677)

Growth Hormone Clinical trials

Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026

TL;DR — MK-677 (Ibutamoren) at a Glance

MK-677 (Ibutamoren) (MK677) is a growth hormone peptide, at the clinical trials stage in the published literature. Orally active growth hormone secretagogue that mimics ghrelin, providing 24-hour GH elevation without injections.

Orally active growth hormone secretagogue that mimics ghrelin, providing 24-hour GH elevation without injections.

Key Data

Research StatusClinical trials
Half-Life24 hours
AdministrationOral
Doses Reported in Published Studies10-25 mg oral

Mechanism of Action

Non-peptide ghrelin mimetic that activates ghrelin receptors orally, causing sustained GH and IGF-1 elevation.

Reported Benefits

Frequently Asked Questions

What is MK-677 (Ibutamoren)?

Orally active growth hormone secretagogue that mimics ghrelin, providing 24-hour GH elevation without injections.

How does MK-677 (Ibutamoren) work?

Non-peptide ghrelin mimetic that activates ghrelin receptors orally, causing sustained GH and IGF-1 elevation.

What is the research status of MK-677 (Ibutamoren)?

MK-677 (Ibutamoren) is at the following stage in the published literature: Clinical trials. All information is for research and educational purposes only.

What is the half-life of MK-677 (Ibutamoren)?

Reported half-life: 24 hours.

How is MK-677 (Ibutamoren) administered in research?

Reported administration route in the literature: Oral. This is not a recommendation for human use.

Educational content, not medical advice. Effects described are drawn from cited research in study subjects.

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