Pentapeptide-18 (PENTA18)

Healing Cosmetic research

Pentapeptide-18 (Leuphasyl) is a synthetic pentapeptide used primarily in cosmetic and dermatological research for its potential anti-wrinkle effects. The peptide is a enkephalin derivative that mimics the mechanism of Waglerin-1, a peptide from temple viper venom. Pentapeptide-18 works by reducing muscle contractions through modulation of neurotransmitter release at the neuromuscular junction. By decreasing the depth of wrinkles caused by repeated facial expressions, it offers a potential alternative approach to botulinum toxin for cosmetic anti-aging applications. The peptide is typically used topically in skincare formulations.

Key Data

Research StatusCosmetic research
Half-LifeUnknown
AdministrationTopical
Typical DosageTopical formulations
Molecular Weight569.65 Da
Molecular FormulaC29H39N5O7

Mechanism of Action

Enkephalin mimetic that reduces muscle tension and promotes skin repair through neuromodulation.

Reported Benefits

All information is presented for Research Use Only (RUO). Not medical advice.

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