Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026
Pentapeptide-18 (PENTA18) is a healing peptide, at the cosmetic research stage in the published literature. Synthetic peptide that mimics enkephalin to reduce muscle contractions and promote skin healing and anti-wrinkle effects.
Synthetic peptide that mimics enkephalin to reduce muscle contractions and promote skin healing and anti-wrinkle effects.
| Research Status | Cosmetic research |
|---|---|
| Half-Life | Unknown |
| Administration | Topical |
| Doses Reported in Published Studies | Topical formulations |
Enkephalin mimetic that reduces muscle tension and promotes skin repair through neuromodulation.
Synthetic peptide that mimics enkephalin to reduce muscle contractions and promote skin healing and anti-wrinkle effects.
Enkephalin mimetic that reduces muscle tension and promotes skin repair through neuromodulation.
Pentapeptide-18 is at the following stage in the published literature: Cosmetic research. All information is for research and educational purposes only.
Reported half-life: Unknown.
Reported administration route in the literature: Topical. This is not a recommendation for human use.
Educational content, not medical advice. Effects described are drawn from cited research in study subjects.