PT-141 (Bremelanotide) (PT141)

Tanning FDA approved

Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026

TL;DR — PT-141 (Bremelanotide) at a Glance

PT-141 (Bremelanotide) (PT141) is a tanning peptide, at the fda approved stage in the published literature. Metabolite of Melanotan II developed specifically for sexual dysfunction. FDA approved as Vyleesi for hypoactive sexual desire disorder.

Metabolite of Melanotan II developed specifically for sexual dysfunction. FDA approved as Vyleesi for hypoactive sexual desire disorder.

Key Data

Research StatusFDA approved
Half-Life2-4 hours
AdministrationSubcutaneous injection
Doses Reported in Published Studies1.75 mg as needed

Mechanism of Action

MC3R and MC4R agonist that acts centrally to increase sexual desire without direct vascular effects.

Reported Benefits

Frequently Asked Questions

What is PT-141 (Bremelanotide)?

Metabolite of Melanotan II developed specifically for sexual dysfunction. FDA approved as Vyleesi for hypoactive sexual desire disorder.

How does PT-141 (Bremelanotide) work?

MC3R and MC4R agonist that acts centrally to increase sexual desire without direct vascular effects.

What is the research status of PT-141 (Bremelanotide)?

PT-141 (Bremelanotide) is at the following stage in the published literature: FDA approved. All information is for research and educational purposes only.

What is the half-life of PT-141 (Bremelanotide)?

Reported half-life: 2-4 hours.

How is PT-141 (Bremelanotide) administered in research?

Reported administration route in the literature: Subcutaneous injection. This is not a recommendation for human use.

Educational content, not medical advice. Effects described are drawn from cited research in study subjects.

← All Peptides Dosing Calculator The Dispatch Home