SS-31 (Elamipretide) (SS31)

Anti-Aging Clinical trials

Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026

TL;DR — SS-31 (Elamipretide) at a Glance

SS-31 (Elamipretide) (SS31) is a anti-aging peptide, at the clinical trials stage in the published literature. Mitochondria-targeted tetrapeptide that improves mitochondrial function and reduces oxidative stress. In clinical trials for heart failure.

Mitochondria-targeted tetrapeptide that improves mitochondrial function and reduces oxidative stress. In clinical trials for heart failure.

Key Data

Research StatusClinical trials
Half-Life~1 hour
AdministrationSubcutaneous or IV injection
Doses Reported in Published Studies0.25-4 mg/kg

Mechanism of Action

Targets cardiolipin in mitochondrial inner membrane, stabilizing electron transport and reducing ROS production.

Reported Benefits

Frequently Asked Questions

What is SS-31 (Elamipretide)?

Mitochondria-targeted tetrapeptide that improves mitochondrial function and reduces oxidative stress. In clinical trials for heart failure.

How does SS-31 (Elamipretide) work?

Targets cardiolipin in mitochondrial inner membrane, stabilizing electron transport and reducing ROS production.

What is the research status of SS-31 (Elamipretide)?

SS-31 (Elamipretide) is at the following stage in the published literature: Clinical trials. All information is for research and educational purposes only.

What is the half-life of SS-31 (Elamipretide)?

Reported half-life: ~1 hour.

How is SS-31 (Elamipretide) administered in research?

Reported administration route in the literature: Subcutaneous or IV injection. This is not a recommendation for human use.

Educational content, not medical advice. Effects described are drawn from cited research in study subjects.

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