Thymosin Beta-4 (TB4)

Healing Clinical trials (cardiac)

Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026

TL;DR — Thymosin Beta-4 at a Glance

Thymosin Beta-4 (TB4) is a healing peptide, at the clinical trials (cardiac) stage in the published literature. The full-length 43 amino acid protein that TB-500 is derived from. Naturally occurring in most tissues and plays key roles in tissue repair.

The full-length 43 amino acid protein that TB-500 is derived from. Naturally occurring in most tissues and plays key roles in tissue repair.

Key Data

Research StatusClinical trials (cardiac)
Half-LifeUnknown
AdministrationSubcutaneous injection
Doses Reported in Published Studies750 mcg - 2 mg

Mechanism of Action

Sequesters G-actin, promotes cell migration, wound healing, and tissue regeneration through multiple pathways.

Reported Benefits

Frequently Asked Questions

What is Thymosin Beta-4?

The full-length 43 amino acid protein that TB-500 is derived from. Naturally occurring in most tissues and plays key roles in tissue repair.

How does Thymosin Beta-4 work?

Sequesters G-actin, promotes cell migration, wound healing, and tissue regeneration through multiple pathways.

What is the research status of Thymosin Beta-4?

Thymosin Beta-4 is at the following stage in the published literature: Clinical trials (cardiac). All information is for research and educational purposes only.

What is the half-life of Thymosin Beta-4?

Reported half-life: Unknown.

How is Thymosin Beta-4 administered in research?

Reported administration route in the literature: Subcutaneous injection. This is not a recommendation for human use.

Educational content, not medical advice. Effects described are drawn from cited research in study subjects.

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