THLN

Thymulin

Immune Anti-Aging Preclinical (animal)

Nonapeptide hormone produced by thymic epithelial cells. Reviews describe its involvement in intra- and extrathymic T-cell differentiation.

Regulatory status (as of Sept 2026)

Not FDA-approved.

See the FDA peptide regulatory tracker · Read our July 27, 2026 dispatch on the FDA PCAC peptide vote
Educational summary. Every effect described below is drawn from the cited published research and describes what was observed in research subjects — not a promise of results, a dose recommendation, or an endorsement for human use. Many peptides are not FDA-approved. Consult a licensed healthcare provider before making any health decision. Full disclaimer.

3 studies referenced · Last reviewed Oct 1, 2026 · Reviewed by The Peptide Dispatch Editorial Team · How we research & label content

TL;DR — Thymulin at a Glance

Thymulin is a compound studied only in animals and lab experiments so far. Nonapeptide hormone produced by thymic epithelial cells.

Half-lifeNot established in published research
How it's given in studiesSubcutaneous injection
Research stagePreclinical (animal)
Dosing
Published research: No published human dosing
detailsNo published human dosing study found; the reviews found describe animal and in vitro work only.
Community-reportedCommunity-reported: 1–10 mcg, subcutaneous injection

Published-research dosing is what was given in the cited studies (species and units as reported). Community-reported dosing is what users describe, not from clinical studies. Neither is a recommendation. Not medical advice.

Where each point comes from: Clinicalhuman trials and FDA labels   Lab / animalrodent, cell and ex vivo studies   Community-reporteduser experience and commonly used protocols, not from clinical studies

How It Works

In plain terms: It is a thymus hormone that needs zinc to work and helps immune T cells develop. Zinc-dependent thymic nonapeptide whose activity depends on bound zinc. Described as inducing T-cell differentiation and enhancing T-cell subset functions in normal or partly thymus-deficient recipients (review, Bach 1989).

Effects Reported in Research

How to read this: Each item below is an effect observed in research subjects in the cited studies — think of Dexter, our stand-in research subject. These are findings from the literature, not results you should expect, and not medical advice.

  • T-cell modulation
  • Lab / animalIn animal studies: immune balance
  • Lab / animalAnti-inflammatory and analgesic effects in the brain in animal studies.

What Users Report (Community, Not Clinical)

Commonly reported protocol

Community-reportedCommonly reported doses range from 1 to 10 mcg (subcutaneous injection). This is not a recommendation.

What users report

  • Community-reportedAutoimmune modulation

Community reports are anecdotal, vary widely in product quality and purity, and are not medical advice. Talk to a licensed provider.

Side Effects and Safety Notes

  • No published human safety data found

References

  1. The thymus-neuroendocrine axis: physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin
    Reggiani PC, Morel GR, Cónsole GM, Barbeito CG, Rodriguez SS, Brown OA et al. Annals of the New York Academy of Sciences. 2009. PMID: 19236333.
    Study type: Review.
    DOI: 10.1111/j.1749-6632.2008.03964.x · PubMed
  2. Thymulin, a zinc-dependent hormone
    Bach JF, Dardenne M. Medical oncology and tumor pharmacotherapy. 1989. PMID: 2657247.
    Study type: Review.
    DOI: 10.1007/BF02985220 · PubMed
  3. Thymulin and the neuroendocrine system
    Goya RG, Brown OA, Pléau JM, Dardenne M. Peptides. 2004. PMID: 15003367.
    Study type: Review.
    DOI: 10.1016/j.peptides.2003.11.002 · PubMed

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How Thymulin Compares

PeptideHalf-LifeRouteResearch Status
ThymulinUnknownSubcutaneous injectionPreclinical (animal)
KPVNo published PK data foundSubcutaneous injection, Oral, TopicalPreclinical (animal)
LL-37UnknownSubcutaneous injectionPhase 2
ThymalinNo published PK data foundIntramuscular injectionApproved outside US
Thymopoietin II Fragment (TP-1)UnknownSubcutaneous injectionPreclinical (animal)

Values reflect figures reported in published research. Compare any peptides side-by-side →

Frequently Asked Questions

What is Thymulin?
Nonapeptide hormone produced by thymic epithelial cells. Reviews describe its involvement in intra- and extrathymic T-cell differentiation.
How does Thymulin work?
In plain terms: It is a thymus hormone that needs zinc to work and helps immune T cells develop. Zinc-dependent thymic nonapeptide whose activity depends on bound zinc. Described as inducing T-cell differentiation and enhancing T-cell subset functions in normal or partly thymus-deficient recipients (review, Bach 1989).
What is the research status of Thymulin?
Thymulin is at the following stage in the published literature: Preclinical (animal). All information is for research and educational purposes only.
What is the half-life of Thymulin?
Reported half-life: Unknown.
How is Thymulin administered in research?
Reported administration route in the literature: Subcutaneous injection. This is not a recommendation for human use.

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Category

This peptide belongs to the Immune category. View All Immune Peptides

Related Categories

Anti-Aging

Related Peptides

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Sources & Methodology

Dosing, half-life figures, and mechanism descriptions on this page are compiled from peer-reviewed published research, with the species and study type stated where reported. Figures labeled “Dosing used in published research” describe what was given in those studies and do not constitute dosing recommendations for any human use. Each cited paper is listed with DOI and PubMed links in the References section above. Found an error? Contact us.

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