P21

Cognitive Preclinical

Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026

TL;DR — P21 at a Glance

P21 is a cognitive peptide, at the preclinical stage in the published literature. Synthetic peptide derived from CNTF that promotes neurogenesis without the appetite-suppressing effects of the parent compound.

Synthetic peptide derived from CNTF that promotes neurogenesis without the appetite-suppressing effects of the parent compound.

Key Data

Research StatusPreclinical
Half-LifeUnknown
AdministrationIntranasal or subcutaneous
Doses Reported in Published Studies100-400 mcg

Mechanism of Action

Promotes neurogenesis and cognitive enhancement through CNTF-related pathways without systemic effects.

Reported Benefits

Frequently Asked Questions

What is P21?

Synthetic peptide derived from CNTF that promotes neurogenesis without the appetite-suppressing effects of the parent compound.

How does P21 work?

Promotes neurogenesis and cognitive enhancement through CNTF-related pathways without systemic effects.

What is the research status of P21?

P21 is at the following stage in the published literature: Preclinical. All information is for research and educational purposes only.

What is the half-life of P21?

Reported half-life: Unknown.

How is P21 administered in research?

Reported administration route in the literature: Intranasal or subcutaneous. This is not a recommendation for human use.

Educational content, not medical advice. Effects described are drawn from cited research in study subjects.

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