P21

Cognitive Preclinical

P21 is a synthetic tetrapeptide derived from Cerebrolysin, designed to mimic the neurotrophic effects of ciliary neurotrophic factor (CNTF). The peptide promotes neurogenesis in the hippocampus and enhances synaptic plasticity, making it a promising compound for cognitive enhancement research. P21 crosses the blood-brain barrier and increases BDNF levels in the brain, stimulating the formation of new neurons and synaptic connections. Unlike larger neurotrophin proteins that cannot penetrate the CNS effectively, P21 small molecular size allows for systemic administration while maintaining neurogenic activity.

Key Data

Research Status
Preclinical
Half-Life
Unknown
Administration
Intranasal or subcutaneous
Typical Dosage
100-400 mcg
Molecular Weight
360.4 Da
Molecular Formula
C14H24N4O7

Mechanism of Action

Promotes neurogenesis and cognitive enhancement through CNTF-related pathways without systemic effects.

Reported Benefits

All information is presented for Research Use Only (RUO). Not medical advice.

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