FOXO4-DRI (FOXO4)

Anti-Aging Early research

Reviewed by The Peptide Dispatch Editorial Team · Last reviewed July 6, 2026

TL;DR — FOXO4-DRI at a Glance

FOXO4-DRI (FOXO4) is a anti-aging peptide, at the early research stage in the published literature. Senolytic peptide that selectively induces apoptosis in senescent cells by disrupting FOXO4-p53 interaction.

Senolytic peptide that selectively induces apoptosis in senescent cells by disrupting FOXO4-p53 interaction.

Key Data

Research StatusEarly research
Half-LifeUnknown
AdministrationSubcutaneous injection
Doses Reported in Published StudiesResearch varies

Mechanism of Action

D-retro-inverso peptide that interferes with FOXO4-p53 binding in senescent cells, triggering their apoptosis.

Reported Benefits

Frequently Asked Questions

What is FOXO4-DRI?

Senolytic peptide that selectively induces apoptosis in senescent cells by disrupting FOXO4-p53 interaction.

How does FOXO4-DRI work?

D-retro-inverso peptide that interferes with FOXO4-p53 binding in senescent cells, triggering their apoptosis.

What is the research status of FOXO4-DRI?

FOXO4-DRI is at the following stage in the published literature: Early research. All information is for research and educational purposes only.

What is the half-life of FOXO4-DRI?

Reported half-life: Unknown.

How is FOXO4-DRI administered in research?

Reported administration route in the literature: Subcutaneous injection. This is not a recommendation for human use.

Educational content, not medical advice. Effects described are drawn from cited research in study subjects.

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