Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively stimulates GH release with minimal effects on cortisol, prolactin, and appetite. Developed by Novo Nordisk, Ipamorelin is often considered the "cleanest" GHRP due to its highly selective action on growth hormone release without significant side effects on other hormonal axes. The peptide binds to the ghrelin receptor (GHS-R1a) but produces a GH release profile more similar to natural GHRH stimulation. Ipamorelin has a favorable safety profile and produces consistent, dose-dependent GH release, making it popular for research applications where specific GH stimulation is desired.
Key Data
Mechanism of Action
Selective GHRP receptor agonist, mimics ghrelin to stimulate pituitary GH release.
Reported Benefits
All information is presented for Research Use Only (RUO). Not medical advice.